BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Intestinal-type alkaline phosphatase' and Ligand = 'BDBM50464736'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intestinal-type alkaline phosphatase


(Homo sapiens (Human))		BDBM50464736
PNG
(CHEMBL4291826)
Show SMILES COc1ccc(cc1)-c1nn2c(nc(cc2=O)C(F)(F)F)s1
Show InChI InChI=1S/C13H8F3N3O2S/c1-21-8-4-2-7(3-5-8)11-18-19-10(20)6-9(13(14,15)16)17-12(19)22-11/h2-6H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 480n/an/an/an/an/an/a



Universit£t Rostock

Curated by ChEMBL


Assay Description
Inhibition of human IAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by ...

Eur J Med Chem 144: 116-127 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.068
BindingDB Entry DOI: 10.7270/Q2W66PDP
More data for this
Ligand-Target Pair