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Found 1 hit Enz. Inhib. hit(s) with Target = 'Intestinal-type alkaline phosphatase' and Ligand = 'BDBM50464738'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intestinal-type alkaline phosphatase


(Homo sapiens (Human))		BDBM50464738
PNG
(CHEMBL4287459)
Show SMILES FC(F)(F)c1cc(=O)n2nc(sc2n1)-c1cccc(c1)C#N
Show InChI InChI=1S/C13H5F3N4OS/c14-13(15,16)9-5-10(21)20-12(18-9)22-11(19-20)8-3-1-2-7(4-8)6-17/h1-5H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.12E+3n/an/an/an/an/an/a



Universit£t Rostock

Curated by ChEMBL


Assay Description
Inhibition of human IAP expressed in COS7 cells preincubated for 5 to 7 mins followed by CDP-star substrate addition measured after 15 to 20 mins by ...

Eur J Med Chem 144: 116-127 (2018)


Article DOI: 10.1016/j.ejmech.2017.11.068
BindingDB Entry DOI: 10.7270/Q2W66PDP
More data for this
Ligand-Target Pair