Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoform Tau-F of Microtubule-associated protein tau' and Ligand = 'BDBM214761'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform Tau-F of Microtubule-associated protein tau (Homo sapiens (Human))	BDBM214761 (Rhodanines, 49A) Show SMILES CC(N1C(=S)N\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O)C([O-])=O Show InChI InChI=1S/C17H13ClN2O4S/c1-9(16(22)23)20-15(21)13(19-17(20)25)8-12-5-6-14(24-12)10-3-2-4-11(18)7-10/h2-9H,1H3,(H,19,25)(H,22,23)/p-1/b13-8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair