Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM186842'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM186842 (US9670157, 19 2,5-Dimethyl-1-(5-methyl-2-phenyl-ox...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)cc2)c(C)n1Cc1csc(c1)-c1cccnc1 Show InChI InChI=1S/C25H26N4OS/c1-17-10-23(25(30)28-13-20-7-5-19(12-26)6-8-20)18(2)29(17)15-21-11-24(31-16-21)22-4-3-9-27-14-22/h3-11,14,16H,12-13,15,26H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM186842 (US9670157, 19 2,5-Dimethyl-1-(5-methyl-2-phenyl-ox...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)cc2)c(C)n1Cc1csc(c1)-c1cccnc1 Show InChI InChI=1S/C25H26N4OS/c1-17-10-23(25(30)28-13-20-7-5-19(12-26)6-8-20)18(2)29(17)15-21-11-24(31-16-21)22-4-3-9-27-14-22/h3-11,14,16H,12-13,15,26H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM186842 (US9670157, 19 2,5-Dimethyl-1-(5-methyl-2-phenyl-ox...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)cc2)c(C)n1Cc1csc(c1)-c1cccnc1 Show InChI InChI=1S/C25H26N4OS/c1-17-10-23(25(30)28-13-20-7-5-19(12-26)6-8-20)18(2)29(17)15-21-11-24(31-16-21)22-4-3-9-27-14-22/h3-11,14,16H,12-13,15,26H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair