Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM186879'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM186879 (US9670157, 45 2,5-Dimethyl-1-(2-phenyl-thiazol-4-y...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)c(F)c2)c(C)n1Cc1csc(n1)-c1ccccc1 Show InChI InChI=1S/C25H25FN4OS/c1-16-10-22(24(31)28-13-18-8-9-20(12-27)23(26)11-18)17(2)30(16)14-21-15-32-25(29-21)19-6-4-3-5-7-19/h3-11,15H,12-14,27H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM186879 (US9670157, 45 2,5-Dimethyl-1-(2-phenyl-thiazol-4-y...) Show SMILES Cc1cc(C(=O)NCc2ccc(CN)c(F)c2)c(C)n1Cc1csc(n1)-c1ccccc1 Show InChI InChI=1S/C25H25FN4OS/c1-16-10-22(24(31)28-13-18-8-9-20(12-27)23(26)11-18)17(2)30(16)14-21-15-32-25(29-21)19-6-4-3-5-7-19/h3-11,15H,12-14,27H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair