Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM187103'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM187103 (US9670157, 117 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4ccc(CN)c(F)c4)c(n3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C25H24F4N6O/c1-16-10-32-34(12-16)13-17-2-4-18(5-3-17)14-35-15-21(23(33-35)25(27,28)29)24(36)31-11-19-6-7-20(9-30)22(26)8-19/h2-8,10,12,15H,9,11,13-14,30H2,1H3,(H,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9834513 (2017) BindingDB Entry DOI: 10.7270/Q2348NPS
					More data for this Ligand-Target Pair
Kallikrein-1 (Homo sapiens (Human))	BDBM187103 (US9670157, 117 1-[4-(4-Methyl-pyrazol-1-ylmethyl)-...) Show SMILES Cc1cnn(Cc2ccc(Cn3cc(C(=O)NCc4ccc(CN)c(F)c4)c(n3)C(F)(F)F)cc2)c1 Show InChI InChI=1S/C25H24F4N6O/c1-16-10-32-34(12-16)13-17-2-4-18(5-3-17)14-35-15-21(23(33-35)25(27,28)29)24(36)31-11-19-6-7-20(9-30)22(26)8-19/h2-8,10,12,15H,9,11,13-14,30H2,1H3,(H,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9670157 (2017) BindingDB Entry DOI: 10.7270/Q2F769QG
					More data for this Ligand-Target Pair