Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM335736'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kallikrein-1 (Homo sapiens (Human))	BDBM335736 (6-{[1-(2-Phenyl-thiazol-4-ylmethyl)-1H-pyrrolo[3,2...) Show SMILES Nc1nccc2cc(CNc3nccc4n(Cc5csc(n5)-c5ccccc5)ccc34)ccc12 Show InChI InChI=1S/C27H22N6S/c28-25-22-7-6-18(14-20(22)8-11-29-25)15-31-26-23-10-13-33(24(23)9-12-30-26)16-21-17-34-27(32-21)19-4-2-1-3-5-19/h1-14,17H,15-16H2,(H2,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kalvista Pharmaceuticals Limited US Patent					Assay Description KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...				US Patent US9738641 (2017) BindingDB Entry DOI: 10.7270/Q2M047K7
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