Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM208987'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208987 (US9233167, a-6-mPEG6-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:32:40:23:38.36.37,28:27:23:38.36.37| Show InChI InChI=1S/C30H47NO10/c1-31-8-7-29-26-22-3-4-23(32)27(26)41-28(29)24(5-6-30(29,33)25(31)21-22)40-20-19-39-18-17-38-16-15-37-14-13-36-12-11-35-10-9-34-2/h3-4,24-25,28,32-33H,5-21H2,1-2H3/t24-,25?,28-,29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	774	-34.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208987 (US9233167, a-6-mPEG6-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:32:40:23:38.36.37,28:27:23:38.36.37| Show InChI InChI=1S/C30H47NO10/c1-31-8-7-29-26-22-3-4-23(32)27(26)41-28(29)24(5-6-30(29,33)25(31)21-22)40-20-19-39-18-17-38-16-15-37-14-13-36-12-11-35-10-9-34-2/h3-4,24-25,28,32-33H,5-21H2,1-2H3/t24-,25?,28-,29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.93E+3	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair