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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50007345'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50007345
PNG
(2-(3,4-Dichloro-phenyl)-N-[1-(2,4-dimethoxy-phenyl...)
Show SMILES COc1ccc(C(CN2CCCC2)N(C)C(=O)Cc2ccc(Cl)c(Cl)c2)c(OC)c1
Show InChI InChI=1S/C23H28Cl2N2O3/c1-26(23(28)13-16-6-9-19(24)20(25)12-16)21(15-27-10-4-5-11-27)18-8-7-17(29-2)14-22(18)30-3/h6-9,12,14,21H,4-5,10-11,13,15H2,1-3H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 248n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand

J Med Chem 34: 3149-58 (1991)


BindingDB Entry DOI: 10.7270/Q2028S53
More data for this
Ligand-Target Pair