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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50007383'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50007383
PNG
(2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-methyl-1-pyr...)
Show SMILES CC(C)C[C@@H](CN1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H28Cl2N2O/c1-14(2)10-16(13-23-8-4-5-9-23)22(3)19(24)12-15-6-7-17(20)18(21)11-15/h6-7,11,14,16H,4-5,8-10,12-13H2,1-3H3/t16-/m0/s1
PDB

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PC sid
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Similars
PubMed
n/an/a 14n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.

J Med Chem 34: 3149-58 (1991)


BindingDB Entry DOI: 10.7270/Q2028S53
More data for this
Ligand-Target Pair