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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50453225'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50453225
PNG
(CHEMBL2310843)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2OCCN=S)ccc3O |r,THB:10:9:4.5.6:17|
Show InChI InChI=1S/C22H28N2O4S/c25-15-4-3-14-11-17-22(26)6-5-16(27-10-8-23-29)20-21(22,18(14)19(15)28-20)7-9-24(17)12-13-1-2-13/h3-4,13,16-17,20,25-26H,1-2,5-12H2/t16-,17-,20+,21+,22-/m1/s1
PDB

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PC sid
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Similars
PubMed
n/an/a 34n/an/an/an/an/an/a



University of Washington

Curated by ChEMBL


Assay Description
Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPE

J Med Chem 35: 2374-84 (1992)


BindingDB Entry DOI: 10.7270/Q2GH9JKS
More data for this
Ligand-Target Pair