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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50458137'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50458137
PNG
(CHEMBL4210742)
Show SMILES COc1ccc(Nc2ccc3CC4C(C)C(C)(CCN4CC4CC4)c3c2)cc1 |TLB:20:19:13:10.24.11,25:24:13:17.18.19|
Show InChI InChI=1S/C25H32N2O/c1-17-24-14-19-6-7-21(26-20-8-10-22(28-3)11-9-20)15-23(19)25(17,2)12-13-27(24)16-18-4-5-18/h6-11,15,17-18,24,26H,4-5,12-14,16H2,1-3H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 0.290n/an/an/an/an/an/an/an/a



University of Catania

Curated by ChEMBL


Assay Description
Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting method

Eur J Med Chem 148: 410-422 (2018)


Article DOI: 10.1016/j.ejmech.2018.02.046
BindingDB Entry DOI: 10.7270/Q2QR50SX
More data for this
Ligand-Target Pair