Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kelch-like ECH-associated protein 1 [321-609] (Homo sapiens (Human)) | BDBM304737![]() (3-(3-((4-ethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd US Patent | Assay Description 100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we... | US Patent US10144731 (2018) BindingDB Entry DOI: 10.7270/Q25X2C17 | |||||||||||
More data for this Ligand-Target Pair |