Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1 [321-609]' and Ligand = 'BDBM304766'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kelch-like ECH-associated protein 1 [321-609] (Homo sapiens (Human))	BDBM304766 ((3R)-3-(1,4-dimethyl-1H-1,2,3-benzotriazol-5-yl)-3...) Show SMILES CN(Cc1cc(ccc1C)[C@@H](CC(O)=O)c1ccc2n(C)nnc2c1C)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C26H28N4O4S/c1-17-10-11-19(14-20(17)16-29(3)35(33,34)21-8-6-5-7-9-21)23(15-25(31)32)22-12-13-24-26(18(22)2)27-28-30(24)4/h5-14,23H,15-16H2,1-4H3,(H,31,32)/t23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd US Patent					Assay Description 100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...				US Patent US10144731 (2018) BindingDB Entry DOI: 10.7270/Q25X2C17
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