Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50165913'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50165913 (CHEMBL3797684) Show SMILES COCCCOc1cc2ncnc(Nc3c(C)c(O)ccc3F)c2cc1OC Show InChI InChI=1S/C20H22FN3O4/c1-12-16(25)6-5-14(21)19(12)24-20-13-9-17(27-3)18(28-8-4-7-26-2)10-15(13)22-11-23-20/h5-6,9-11,25H,4,7-8H2,1-3H3,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of recombinant KIF5B/RET (unknown origin) expressed in IL3 deficient BAF3 cells assessed as reduction in cell viability after 48 hrs by Ce...				Bioorg Med Chem Lett 26: 2724-9 (2016) Article DOI: 10.1016/j.bmcl.2016.03.100 BindingDB Entry DOI: 10.7270/Q2WM1G93
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