Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM50316145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50316145 (CHEMBL4176343) Show SMILES CC(=O)Nc1ncnc(N2CCCC(C2)NC(=O)c2cccc(c2)C(F)(F)F)c1-c1ccccc1 Show InChI InChI=1S/C25H24F3N5O2/c1-16(34)31-22-21(17-7-3-2-4-8-17)23(30-15-29-22)33-12-6-11-20(14-33)32-24(35)18-9-5-10-19(13-18)25(26,27)28/h2-5,7-10,13,15,20H,6,11-12,14H2,1H3,(H,32,35)(H,29,30,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alagappa University Curated by ChEMBL					Assay Description Inhibition of human mitotic kinesin Eg5 motor domain (1 to 368 residues) assessed as reduction in steady-state basal ATPase activity using ATP as sub...				Eur J Med Chem 148: 106-115 (2018) Article DOI: 10.1016/j.ejmech.2018.02.010 BindingDB Entry DOI: 10.7270/Q25141R9
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