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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF18A' and Ligand = 'BDBM50404030'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF18A


(Homo sapiens)		BDBM50404030
PNG
(CHEMBL5278809)
Show SMILES OC(=O)c1cc(ccc1C1C2C=CC(=O)C=C2Oc2cc(O)ccc12)C(=O)NCCCCNC(NCCCOc1cccc(CN2CCCCC2)c1)=NC#N |w:52.58,c:12,16|
Show InChI InChI=1S/C42H46N6O7/c43-27-47-42(46-18-7-21-54-32-9-6-8-28(22-32)26-48-19-4-1-5-20-48)45-17-3-2-16-44-40(51)29-10-13-33(36(23-29)41(52)53)39-34-14-11-30(49)24-37(34)55-38-25-31(50)12-15-35(38)39/h6,8-15,22-25,34,39,50H,1-5,7,16-21,26H2,(H,44,51)(H,52,53)(H2,45,46,47)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
n/an/a 140n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.

Citation and Details
More data for this
Ligand-Target Pair