Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynurenine 3-monooxygenase (Rattus norvegicus) | BDBM50072260 ((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Inhibition of rat brain KYN 3-OHase. | Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynurenine 3-monooxygenase (Rattus norvegicus) | BDBM50072260 ((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver | J Med Chem 43: 123-7 (2000) BindingDB Entry DOI: 10.7270/Q2RX9B9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kynurenine 3-monooxygenase (Rattus norvegicus) | BDBM50072260 ((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia& Upjohn Curated by ChEMBL | Assay Description Inhibition of rat liver KYN 3-OHase. | Bioorg Med Chem Lett 8: 2907-12 (1999) BindingDB Entry DOI: 10.7270/Q23X874K | |||||||||||
More data for this Ligand-Target Pair |