BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Legumain' and Ligand = 'BDBM50510322'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Legumain


(Homo sapiens (Human))		BDBM50510322
PNG
(CHEMBL4571494)
Show SMILES CC(C)(CS(=O)(=O)c1ccc(cc1)-c1cc(F)cc(F)c1)C(=O)N[C@@H](CC(N)=O)C#N |r|
Show InChI InChI=1S/C21H21F2N3O4S/c1-21(2,20(28)26-17(11-24)10-19(25)27)12-31(29,30)18-5-3-13(4-6-18)14-7-15(22)9-16(23)8-14/h3-9,17H,10,12H2,1-2H3,(H2,25,27)(H,26,28)/t17-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Queen's University Belfast

Curated by ChEMBL


Assay Description
Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-AMC as substrate measured for every 2 mins for 60 mins by fluorescence-based microplate ...

Bioorg Med Chem Lett 29: 1546-1548 (2019)


Article DOI: 10.1016/j.bmcl.2019.03.019
BindingDB Entry DOI: 10.7270/Q2CV4N2X
More data for this
Ligand-Target Pair