Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM384432'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384432 (US10590114, No. 118 | US11111235, Compound 118 | U...) Show SMILES CCNc1nc(Nc2cn(nc2C2CC2)C(C)(C)C#N)ncc1C(F)(F)F Show InChI InChI=1S/C17H20F3N7/c1-4-22-14-11(17(18,19)20)7-23-15(25-14)24-12-8-27(16(2,3)9-21)26-13(12)10-5-6-10/h7-8,10H,4-6H2,1-3H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair