Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM384457'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384457 (US10590114, No. 144 | US11111235, Compound 143 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM384457 (US10590114, No. 144 | US11111235, Compound 143 | U...) Show SMILES CCNc1nc(Nc2cc(nn2C2CC2)C2(C)CCOC2=O)ncc1C(F)(F)F Show InChI InChI=1S/C18H21F3N6O2/c1-3-22-14-11(18(19,20)21)9-23-16(25-14)24-13-8-12(26-27(13)10-4-5-10)17(2)6-7-29-15(17)28/h8-10H,3-7H2,1-2H3,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
Denali Therapautics Inc. US Patent					Assay Description Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well...				US Patent US10590114 (2020) BindingDB Entry DOI: 10.7270/Q2DJ5JNW
					More data for this Ligand-Target Pair