Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM410700'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410700 (US10377772, Compound N1) Show SMILES C1C[C@H]2COc3cccc(c3)-c3cnn4ccc(NCCN2C1)nc34 |r| Show InChI InChI=1S/C19H21N5O/c1-3-14-11-16(5-1)25-13-15-4-2-8-23(15)10-7-20-18-6-9-24-19(22-18)17(14)12-21-24/h1,3,5-6,9,11-12,15H,2,4,7-8,10,13H2,(H,20,22)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
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