Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM410723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410723 (US10377772, Compound N24) Show SMILES CN1CCN2CCN(C)c3ccn4ncc(-c5cc(OC[C@@H]2C1)ccc5F)c4n3 |r| Show InChI InChI=1S/C21H25FN6O/c1-25-7-9-27-10-8-26(2)20-5-6-28-21(24-20)18(12-23-28)17-11-16(3-4-19(17)22)29-14-15(27)13-25/h3-6,11-12,15H,7-10,13-14H2,1-2H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
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