Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM410724'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410724 (US10377772, Compound N25) Show SMILES CN1CCN2CCOC[C@H]2COc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C20H22FN5O2/c1-24-6-7-25-8-9-27-12-14(25)13-28-15-2-3-18(21)16(10-15)17-11-22-26-5-4-19(24)23-20(17)26/h2-5,10-11,14H,6-9,12-13H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
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