Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM410730'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410730 (US10377772, Compound N31) Show SMILES CN1CCN2C[C@@H]3CCCN3C[C@@H](C2)Oc2ccc(F)c(c2)-c2cnn3ccc1nc23 |r| Show InChI InChI=1S/C23H27FN6O/c1-27-9-10-28-13-16-3-2-7-29(16)15-18(14-28)31-17-4-5-21(24)19(11-17)20-12-25-30-8-6-22(27)26-23(20)30/h4-6,8,11-12,16,18H,2-3,7,9-10,13-15H2,1H3/t16-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
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