Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM410733'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410733 (US10377772, Compound N34) Show SMILES CN1CCN2CCC(CC2)Oc2ccc(F)c(c2)-c2cnn3ccc1nc23 |(-4.69,2.44,;-3.35,1.67,;-3.35,.13,;-4.69,-.64,;-4.69,-2.18,;-5.09,-3.66,;-4,-4.75,;-2.51,-4.35,;-2.11,-2.87,;-3.2,-1.78,;.73,-3.19,;1.82,-2.1,;3.31,-2.5,;4.4,-1.41,;4,.08,;5.09,1.17,;2.51,.48,;1.42,-.61,;2.11,1.97,;3.02,3.21,;2.11,4.46,;.65,3.98,;-.69,4.75,;-2.02,3.98,;-2.02,2.44,;-.69,1.67,;.65,2.44,)| Show InChI InChI=1S/C20H22FN5O/c1-24-10-11-25-7-4-14(5-8-25)27-15-2-3-18(21)16(12-15)17-13-22-26-9-6-19(24)23-20(17)26/h2-3,6,9,12-14H,4-5,7-8,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
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