Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM410739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM410739 (US10377772, Compound N40) Show SMILES C[C@H]1C[C@@H]2CCN1CCNc1ccn3ncc(-c4cc(O2)ccc4F)c3n1 |r| Show InChI InChI=1S/C20H22FN5O/c1-13-10-15-4-7-25(13)9-6-22-19-5-8-26-20(24-19)17(12-23-26)16-11-14(27-15)2-3-18(16)21/h2-3,5,8,11-13,15H,4,6-7,9-10H2,1H3,(H,22,24)/t13-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Oncodesign S.A. US Patent					Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k...				US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ
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