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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM50507678'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM50507678
PNG
(CHEMBL4560272)
Show SMILES CCc1cc(nn1C)-c1n[nH]c2ccnc(NC(C)C)c12
Show InChI InChI=1S/C15H20N6/c1-5-10-8-12(20-21(10)4)14-13-11(18-19-14)6-7-16-15(13)17-9(2)3/h6-9H,5H2,1-4H3,(H,16,17)(H,18,19)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3.5n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in insect cells using RtGWWRFYTLRRAR...

Bioorg Med Chem Lett 29: 674-680 (2019)


Article DOI: 10.1016/j.bmcl.2018.10.017
BindingDB Entry DOI: 10.7270/Q2HH6PCX
More data for this
Ligand-Target Pair