Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S]' and Ligand = 'BDBM523034'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] (Homo sapiens (Human))	BDBM523034 (US11161854, Example 2.7-1 | US11161854, Example 2....) Show SMILES CNc1nc(cc(n1)-n1ncc2ccc(cc12)C1(CC11CC1)C#N)N1CC2(CC1C2)C(C)(C)O |THB:4:24:27:29,(-4.92,1.29,;-3.89,.15,;-2.38,.47,;-1.9,1.93,;-.4,2.25,;.63,1.11,;.16,-.36,;-1.35,-.68,;1.19,-1.5,;2.72,-1.34,;3.35,-2.75,;2.2,-3.78,;2.2,-5.32,;.87,-6.09,;-.47,-5.32,;-.47,-3.78,;.87,-3.01,;-1.8,-6.09,;-3.32,-6.36,;-2.79,-4.91,;-3.78,-3.73,;-2.26,-3.46,;-1.27,-7.54,;-.75,-8.98,;.08,3.72,;-.9,4.84,;.59,5.2,;1.96,6,;1.49,4.04,;2.93,3.48,;.02,6.63,;-.56,8.06,;1.44,7.21,;-1.41,6.05,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, C...				Citation and Details BindingDB Entry DOI: 10.7270/Q29K4FC3
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 [1-1200,1251-2527,G2019S] (Homo sapiens (Human))	BDBM523034 (US11161854, Example 2.7-1 | US11161854, Example 2....) Show SMILES CNc1nc(cc(n1)-n1ncc2ccc(cc12)C1(CC11CC1)C#N)N1CC2(CC1C2)C(C)(C)O |THB:4:24:27:29,(-4.92,1.29,;-3.89,.15,;-2.38,.47,;-1.9,1.93,;-.4,2.25,;.63,1.11,;.16,-.36,;-1.35,-.68,;1.19,-1.5,;2.72,-1.34,;3.35,-2.75,;2.2,-3.78,;2.2,-5.32,;.87,-6.09,;-.47,-5.32,;-.47,-3.78,;.87,-3.01,;-1.8,-6.09,;-3.32,-6.36,;-2.79,-4.91,;-3.78,-3.73,;-2.26,-3.46,;-1.27,-7.54,;-.75,-8.98,;.08,3.72,;-.9,4.84,;.59,5.2,;1.96,6,;1.49,4.04,;2.93,3.48,;.02,6.63,;-.56,8.06,;1.44,7.21,;-1.41,6.05,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, C...				Citation and Details BindingDB Entry DOI: 10.7270/Q29K4FC3
					More data for this Ligand-Target Pair