Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 [970-2527] (Homo sapiens (Human)) | BDBM239522 (US9416126, U6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.16 | n/a | n/a | n/a | n/a | 8.5 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description a) 400 nl of a 1:2.15 serial dilution of test compound(98 μM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well... | US Patent US9416126 (2016) BindingDB Entry DOI: 10.7270/Q2D50KV9 | |||||||||||
More data for this Ligand-Target Pair |