Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 [970-2527] (Homo sapiens (Human)) | BDBM254935 (US9499542, 18 | US9675594, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 358 | n/a | n/a | n/a | n/a |
NMMLSC US Patent | Assay Description In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th... | US Patent US9675594 (2017) BindingDB Entry DOI: 10.7270/Q2ZC8110 | |||||||||||
More data for this Ligand-Target Pair |