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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucyl-cystinyl aminopeptidase' and Ligand = 'BDBM50478355'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucyl-cystinyl aminopeptidase


(Homo sapiens (Human))		BDBM50478355
PNG
(CHEMBL258642)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)C1(CN)CCCC1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C42H56N8O8/c1-3-26(2)35(49-36(52)31(20-28-13-15-30(51)16-14-28)48-41(58)42(24-43)17-7-8-18-42)38(54)46-32(22-29-23-44-25-45-29)39(55)50-19-9-12-34(50)37(53)47-33(40(56)57)21-27-10-5-4-6-11-27/h4-6,10-11,13-16,23,25-26,31-35,51H,3,7-9,12,17-22,24,43H2,1-2H3,(H,44,45)(H,46,54)(H,47,53)(H,48,58)(H,49,52)(H,56,57)/t26-,31-,32-,33-,34-,35-/m0/s1
PDB

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KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
 2.14E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit Brussel

Curated by ChEMBL


Assay Description
Inhibition of human recombinant IRAP expressed in HEK293 cells

J Med Chem 51: 2291-6 (2008)


Article DOI: 10.1021/jm701490g
BindingDB Entry DOI: 10.7270/Q25M68HP
More data for this
Ligand-Target Pair