Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Leukotriene A-4 hydrolase' and Ligand = 'BDBM50343910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343910 (2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyrazine |...) Show SMILES C(CN1CCCC1)Oc1ccc(Oc2cnccn2)cc1 Show InChI InChI=1S/C16H19N3O2/c1-2-10-19(9-1)11-12-20-14-3-5-15(6-4-14)21-16-13-17-7-8-18-16/h3-8,13H,1-2,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50343910 (2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyrazine |...) Show SMILES C(CN1CCCC1)Oc1ccc(Oc2cnccn2)cc1 Show InChI InChI=1S/C16H19N3O2/c1-2-10-19(9-1)11-12-20-14-3-5-15(6-4-14)21-16-13-17-7-8-18-16/h3-8,13H,1-2,9-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISA				J Med Chem 54: 3650-60 (2011) Article DOI: 10.1021/jm200063s BindingDB Entry DOI: 10.7270/Q24M94WS
					More data for this Ligand-Target Pair