Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lys-gingipain' and Ligand = 'BDBM453308'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lys-gingipain (Porphyromonas gingivalis)	BDBM453308 (US10730826, Compound 8a | US11325884, Compound 8a) Show SMILES NCCCCC(NC(=O)C1CCCC1)C(=O)COc1cc(F)cc(F)c1 Show InChI InChI=1S/C19H26F2N2O3/c20-14-9-15(21)11-16(10-14)26-12-18(24)17(7-3-4-8-22)23-19(25)13-5-1-2-6-13/h9-11,13,17H,1-8,12,22H2,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...				Citation and Details BindingDB Entry DOI: 10.7270/Q2GF0XQ1
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