Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM264006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264006 (2-[5-[(4-fluorophenyl)methoxy]-4- methylpyrazol-1-...) Show SMILES Cc1cnn(c1OCc1ccc(F)cc1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C17H14FN3O3/c1-11-9-20-21(15-8-13(17(22)23)6-7-19-15)16(11)24-10-12-2-4-14(18)5-3-12/h2-9H,10H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264006 (2-[5-[(4-fluorophenyl)methoxy]-4- methylpyrazol-1-...) Show SMILES Cc1cnn(c1OCc1ccc(F)cc1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C17H14FN3O3/c1-11-9-20-21(15-8-13(17(22)23)6-7-19-15)16(11)24-10-12-2-4-14(18)5-3-12/h2-9H,10H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				J Med Chem 50: 3359-68 (2007) BindingDB Entry DOI: 10.7270/Q29Z9762
					More data for this Ligand-Target Pair