Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM281089![]() (US10022354, Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: liang.jun@gene.com. Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal FLAG-tagged KDM5B expressed in baculovirus infected Sf9 insect cells using H3K4me3 peptide as substrate af... | Bioorg Med Chem Lett 27: 2974-2981 (2017) Article DOI: 10.1016/j.bmcl.2017.05.016 BindingDB Entry DOI: 10.7270/Q2RF5XFT | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM281089![]() (US10022354, Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM281089![]() (US10022354, Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00797 BindingDB Entry DOI: 10.7270/Q2GX4GJR | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |