Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM50483926' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysine-specific demethylase 5B
(Homo sapiens (Human)) | BDBM50483926
![PNG](/data/jpeg/tenK5048/BindingDB_50483926.png) (CHEMBL5285505)Show SMILES [H][C@@]1(O[C@@H]2\C=C(C)\C\C=C(C)\C(=O)O[C@@H]([C@@H](C)\C=C\C=C(C)\[C@@H](OC)[C@@H](C)[C@H](O)\C=C\C(\C)=C/C(/CO)=C\[C@@H]2C)c2csc(n2)[C@H](CC(C)C)OC(=O)NC)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r,c:4,8,19,32,36,t:17,29| Show InChI InChI=1S/C48H72N2O13S/c1-26(2)19-38(62-48(58)49-10)45-50-35(25-64-45)44-30(6)14-12-13-29(5)43(59-11)33(9)36(53)18-16-27(3)20-34(23-51)22-32(8)37(21-28(4)15-17-31(7)46(57)63-44)60-47-42(56)41(55)40(54)39(24-52)61-47/h12-14,16-18,20-22,25-26,30,32-33,36-44,47,51-56H,15,19,23-24H2,1-11H3,(H,49,58)/b14-12+,18-16+,27-20-,28-21+,29-13+,31-17+,34-22+/t30-,32-,33-,36+,37+,38-,39+,40+,41-,42+,43+,44-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| KEGG PC cid PC sid UniChem
| | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Lysine-specific demethylase 5B
(Homo sapiens (Human)) | BDBM50483926
![PNG](/data/jpeg/tenK5048/BindingDB_50483926.png) (CHEMBL5285505)Show SMILES [H][C@@]1(O[C@@H]2\C=C(C)\C\C=C(C)\C(=O)O[C@@H]([C@@H](C)\C=C\C=C(C)\[C@@H](OC)[C@@H](C)[C@H](O)\C=C\C(\C)=C/C(/CO)=C\[C@@H]2C)c2csc(n2)[C@H](CC(C)C)OC(=O)NC)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r,c:4,8,19,32,36,t:17,29| Show InChI InChI=1S/C48H72N2O13S/c1-26(2)19-38(62-48(58)49-10)45-50-35(25-64-45)44-30(6)14-12-13-29(5)43(59-11)33(9)36(53)18-16-27(3)20-34(23-51)22-32(8)37(21-28(4)15-17-31(7)46(57)63-44)60-47-42(56)41(55)40(54)39(24-52)61-47/h12-14,16-18,20-22,25-26,30,32-33,36-44,47,51-56H,15,19,23-24H2,1-11H3,(H,49,58)/b14-12+,18-16+,27-20-,28-21+,29-13+,31-17+,34-22+/t30-,32-,33-,36+,37+,38-,39+,40+,41-,42+,43+,44-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| KEGG PC cid PC sid UniChem
| | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |