Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A [151-852]' and Ligand = 'BDBM103879'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM103879 (US9695167, 6) Show SMILES Cc1ccc(cc1)-c1c(cc(-c2cccc(CN3CCNCC3)c2)c2ncnn12)-c1ccc(cc1)C#N Show InChI InChI=1S/C31H28N6/c1-22-5-9-26(10-6-22)30-28(25-11-7-23(19-32)8-12-25)18-29(31-34-21-35-37(30)31)27-4-2-3-24(17-27)20-36-15-13-33-14-16-36/h2-12,17-18,21,33H,13-16,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695167 (2017) BindingDB Entry DOI: 10.7270/Q2XP7334
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