Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysosomal Pro-X carboxypeptidase' and Ligand = 'BDBM126715'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM126715 (US8785634, 21) Show SMILES OC(=O)C(N1CCC2(CC1)OC(c1cccnc21)c1cc(Cl)cc(Cl)c1)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C26H21Cl2F3N2O4/c27-17-12-16(13-18(28)14-17)22-20-2-1-9-32-23(20)25(37-22)7-10-33(11-8-25)21(24(34)35)15-3-5-19(6-4-15)36-26(29,30)31/h1-6,9,12-14,21-22H,7-8,10-11H2,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp US Patent					Assay Description The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...				US Patent US8785634 (2014) BindingDB Entry DOI: 10.7270/Q2HH6HRS
					More data for this Ligand-Target Pair