Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM285828'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM285828 ((6R,7R,8S)-6,7-dihydroxy-N-methyl-4-azaspiro[2.5]o...) Show SMILES CNC(=O)[C@@H]1[C@@H](O)[C@H](O)CNC11CC1 |r| Show InChI InChI=1S/C9H16N2O3/c1-10-8(14)6-7(13)5(12)4-11-9(6)2-3-9/h5-7,11-13H,2-4H2,1H3,(H,10,14)/t5-,6+,7+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
Alectos Therapeutics Inc. US Patent					Assay Description Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...				US Patent US9796680 (2017) BindingDB Entry DOI: 10.7270/Q2SN0C36
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM285828 ((6R,7R,8S)-6,7-dihydroxy-N-methyl-4-azaspiro[2.5]o...) Show SMILES CNC(=O)[C@@H]1[C@@H](O)[C@H](O)CNC11CC1 |r| Show InChI InChI=1S/C9H16N2O3/c1-10-8(14)6-7(13)5(12)4-11-9(6)2-3-9/h5-7,11-13H,2-4H2,1H3,(H,10,14)/t5-,6+,7+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	264	n/a	n/a	n/a	n/a	7.0	n/a
Alectos Therapeutics Inc. US Patent					Assay Description Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...				US Patent US10081601 (2018) BindingDB Entry DOI: 10.7270/Q2S184JZ
					More data for this Ligand-Target Pair