Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM84608 (2,4-diamino-6-nitro-quinazoline, 1a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Research Institute, Hospital for Sick Children | Assay Description Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc. | Chembiochem 9: 2650-62 (2008) Article DOI: 10.1002/cbic.200800304 BindingDB Entry DOI: 10.7270/Q2JQ0ZJK | |||||||||||
More data for this Ligand-Target Pair |