Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysosomal protective protein' and Ligand = 'BDBM156799'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal protective protein (Homo sapiens (Human))	BDBM156799 (US9029559, 230) Show SMILES COc1ccc(nc1-c1cc(F)ccc1C)C(=O)N[C@@H](CC(O)=O)c1ccc(C)cc1 Show InChI InChI=1S/C24H23FN2O4/c1-14-4-7-16(8-5-14)20(13-22(28)29)27-24(30)19-10-11-21(31-3)23(26-19)18-12-17(25)9-6-15(18)2/h4-12,20H,13H2,1-3H3,(H,27,30)(H,28,29)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	111	n/a	n/a	n/a	n/a	5.5	25
SANOFI US Patent					Assay Description The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...				US Patent US9029559 (2015) BindingDB Entry DOI: 10.7270/Q22V2DW7
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