Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysosomal protective protein' and Ligand = 'BDBM157062'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal protective protein (Homo sapiens (Human))	BDBM157062 (US9029559, 515) Show SMILES Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1nc(Cl)c(N)nc1N Show InChI InChI=1S/C15H16ClN5O3/c1-7-4-2-3-5-8(7)9(6-10(22)23)19-15(24)11-13(17)21-14(18)12(16)20-11/h2-5,9H,6H2,1H3,(H,19,24)(H,22,23)(H4,17,18,21)/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	87.1	n/a	n/a	n/a	n/a	5.5	25
SANOFI US Patent					Assay Description The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...				US Patent US9029559 (2015) BindingDB Entry DOI: 10.7270/Q22V2DW7
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