Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysosomal protective protein' and Ligand = 'BDBM157118'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal protective protein (Homo sapiens (Human))	BDBM157118 (US9029559, 602) Show SMILES OC(=O)C[C@H](NC(=O)c1cccc(n1)-c1ccccc1Cl)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H16Cl2N2O3/c22-14-10-8-13(9-11-14)19(12-20(26)27)25-21(28)18-7-3-6-17(24-18)15-4-1-2-5-16(15)23/h1-11,19H,12H2,(H,25,28)(H,26,27)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	62.3	n/a	n/a	n/a	n/a	5.5	25
SANOFI US Patent					Assay Description The activated cathepsin A was diluted in assay buffer (25 mM MES, pH 5.5, containing 5 mM DTT) and mixed with the test compound (dissolved in assay b...				US Patent US9029559 (2015) BindingDB Entry DOI: 10.7270/Q22V2DW7
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