Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 [41-364] (Homo sapiens (Human))	BDBM30225 (carboline analog, 37) Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nccs1 Show InChI InChI=1S/C16H14N4O2S/c1-8-7-18-15(22)13-12(8)10-6-9(2-3-11(10)19-13)14(21)20-16-17-4-5-23-16/h2-6,8,19H,7H2,1H3,(H,18,22)(H,17,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	7.6	25
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
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