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Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30240'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-activated protein kinase 2 [41-364]


(Homo sapiens (Human))
BDBM30240
PNG
(carboline analog, 52)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C19H16ClN3O2/c1-10-9-21-19(25)17-16(10)14-7-11(5-6-15(14)23-17)18(24)22-13-4-2-3-12(20)8-13/h2-8,10,23H,9H2,1H3,(H,21,25)(H,22,24)
PDB
MMDB

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Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair