Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30255'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 [41-364] (Homo sapiens (Human))	BDBM30255 (carboline analog, 67) Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccc(cc1)C(N)=O Show InChI InChI=1S/C20H18N4O3/c1-10-9-22-20(27)17-16(10)14-8-12(4-7-15(14)24-17)19(26)23-13-5-2-11(3-6-13)18(21)25/h2-8,10,24H,9H2,1H3,(H2,21,25)(H,22,27)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
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