Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30269'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 [41-364] (Homo sapiens (Human))	BDBM30269 (carboline analog, 81) Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NCCO Show InChI InChI=1S/C19H19N5O4S/c1-9-7-21-18(28)15-14(9)11-6-10(2-3-12(11)22-15)16(26)24-19-23-13(8-29-19)17(27)20-4-5-25/h2-3,6,8-9,22,25H,4-5,7H2,1H3,(H,20,27)(H,21,28)(H,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair				3D Structure (docked)