Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 [41-364] (Homo sapiens (Human))	BDBM30280 (indole-based 6-membered lactam, 3d) Show SMILES OCC1Cc2c([nH]c3ccc(cc23)C(=O)Nc2nccs2)C(=O)N1 Show InChI InChI=1S/C16H14N4O3S/c21-7-9-6-11-10-5-8(14(22)20-16-17-3-4-24-16)1-2-12(10)19-13(11)15(23)18-9/h1-5,9,19,21H,6-7H2,(H,18,23)(H,17,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.6	25
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 18: 1994-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.119 BindingDB Entry DOI: 10.7270/Q2ZW1J8V
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