Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30298'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 [41-364] (Homo sapiens (Human))	BDBM30298 (indole-based 7-membered lactam, 23a) Show SMILES O=C(Nc1cccnc1)c1ccc2cc3C(=O)NCCCn3c2c1 Show InChI InChI=1S/C18H16N4O2/c23-17(21-14-3-1-6-19-11-14)13-5-4-12-9-16-18(24)20-7-2-8-22(16)15(12)10-13/h1,3-6,9-11H,2,7-8H2,(H,20,24)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 18: 1994-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.119 BindingDB Entry DOI: 10.7270/Q2ZW1J8V
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